Are Lactobacillus Bulgaricus and Bacillus Calmette-Guérin vaccine suitable for patient protection against SARS-CoV-2 infection?

Abstract Before COVID-19 infection caused the global pandemic in 2020, coronavirus diseases were mainly of veterinary interest. This necessitated development protective and therapeutic measures against spread SARS-CoV-2. Foods containing representatives genus Lactobacillus are an integral part daily menu Bulgarian people. Our hypothesis is based on studies examining its potential for competitive inhibition viruses bacteria by attachment to surface enterocytes. Bacillus Calmette-Guérin (BCG) vaccination calendar Republic Bulgaria. In literature, many clinical show that administration BCG vaccine limits SARS-CoV-2 antigens and, consequently, able induce protection COVID-19, activating specific, innate immune system. The lack definitively approved treatment necessitates finding ways limit until final drug approval. We believe use dietary components context schedule coronavirus-related applicable. hypothesize may play a effect alone or combination healthy individuals.